Foscarnet Price, Uses, Side Effects & Warnings

 


Foscarnet- An Overview: 

Foscarnet is authorized as an antiviral agent. The medicine shows activity against human herpesviruses and HIV. It is used for the treatment of eye complications caused by CMV in individuals with AIDS. The drug is also used for the treatment of a type of HSV that cannot be treated by another drug in individuals with a weak immune system. Foscarnet sodium is supplied under the brand name Foscavir, which is an organic analogue of inorganic pyrophosphate that blocks the imitation of herpesviruses in vitro including CMV and HSV types 1 and 2. This medicinal product exerts its antiviral action by a selective blockage at the pyrophosphate binding site on virus-specific DNA polymerases at concentrations that do not impact cellular DNA polymerases. Foscarnet does not need activation by thymidine kinase or other kinases and therefore is enabled in vitro against HSV TK deficient mutants and CMV UL97 mutants. Thus, CMV strains resistant to ganciclovir or HSV strains resistant to acyclovir may be sensitive to this medicine.


Foscarnet Uses, Side Effects & Warnings

Foscarnet Uses:

  • CMV retinitis or Cytomegalovirus retinitis in individuals with acquired immunodeficiency syndrome (AIDS).

  • Aciclovir resistant HSV infections in immunocompromised individuals. The safety and efficacy of this medicine to treat other HSV infections (e.g. retinitis, encephalitis); congenital or neonatal disease; or HSV in immunocompetent individuals have not been established.


Foscarnet Side Effects: The commonly reported side effects of foscarnet injection may include:

  • fever

  • flu-like symptoms

  • nausea

  • vomiting

  • diarrhea

  • headache

  • chest pain

  • back pain


Seek immediate medical assistance if you have signs of an allergic reaction: difficulty breathing; hives; swelling of the face, lips, tongue, or throat.


Foscarnet (Foscavir) may also be responsible for causing serious side effects. Call your health specialist at once in case you have:

  • convulsions;

  • pain or burning while urination;

  • headache with chest pain and serious dizziness, fainting, quick or pounding heartbeats;

  • low WBC counts; fever, painful mouth sores, swollen gums, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing;

  • low RBCs (anemia); pale skin, fast heart rate, feeling light-headed, trouble concentrating;

  • low calcium; numbness or tingly feeling around mouth, muscle tightness or contraction, fast or slow heart rate, overactive reflexes;

  • low potassium; constipation, muscle weakness, numbness or tingling, tiredness, slow heart rate, fainting; or

  • kidney problems; painful or difficult urination; little or no urinating; swelling in your feet or ankles; shortness of breath or feeling tired.


Foscarnet Warnings:

  • Use foscarnet 24mg/mL in 250 mL with caution in those with reduced renal function. Since renal function impairment may emerge at any juncture during the use of foscarnet, serum creatinine needs to be evaluated every second day throughout induction therapy and once a week during maintenance therapy.

  • Patients with a history of existing prolongation of cardiac conduction intervals, mainly QTc, in those with significant electrolyte disturbances or bradycardia, as well as those with underlying cardiac complications, must be monitored due to a higher risk for ventricular arrhythmia.

  • Foscarnet sodium is excreted in intense concentrations in human urine and may be related to genital irritation or ulceration. In order to prevent irritation or ulceration, precise attention to personal hygiene is needed and cleaning of the genital parts/area after each micturition is required.


Foscarnet Price in India:

Foscarnet price in India is low. If you are looking to smooth access/buy foscarnet 24mg/mL in 250 mL injection at the best price from India, then we can be your one-stop solution. Kindly dial our TOLL-FREE: 1800-889-1064. We are a WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Exporter/ Importer and Supplier of Foscarnet 24mg/mL in 250 mL injection from India. This medicinal product is available in a strength of 24mg/mL in 250 mL.

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